Design and Development of Toroidal Core Winding Machine with Digital Interface

The small size and inherent superior electrical characteristics of a toroid has made it the first choice for many Original Equipment Manufacturers (OEMs). However, the lack of knowledge regarding the toroidal coil winding equipment is still hampering the growth of toroid as the first choice for transformers, inductors and other electrical applications. Additionally, due to Covid-19 pandemic and lockdown situation, small scale companies are lacking skilled manpower for the high precision task of toroidal core winding and taping. Although the machine is readily available in the market, the cost is still very high. Toroidal core winding machine is an equipment used for the purpose of winding toroidal cores which is used in various electrical machines such as current transformers, power transformers, isolation transformers, inductors and chokes, auto transformers, etc. This project aims to develop a low-cost toroidal winding machine with a user-friendly digital interface for selection of winding parameters as per the user input. The winding machine developed in this project is efficient and reliable with high-speed performance and negligible error. © 2022 IEEE.

How to dissect viral infections and their interplay with the host-proteome by immunoaffinity and mass spectrometry: A tutorial

[Display omitted] • Immunohistochemistry with magnetic core nanoparticles to isolate viruses. • The use of MALDI-MS for rapid virus detection is explained in detail. • The use of ESI-MS/MS to pinpoint host-patient crosstalk is explained in detail. • The absolute quantitative MS is explained for large-scale protein quantitation. The capabilities of bioanalytical mass spectrometry to (i) detect and differentiate viruses at the peptide level whilst maintaining high sample throughput and (ii) to provide diagnosis and prognosis for infected patients are presented as a tutorial in this work to aid analytical chemists and physicians to gain insights into the possibilities offered by current high-resolution mass spectrometry technology and bioinformatics. From (i) sampling to sample treatment;(ii) Matrix-Assisted Laser Desorption Ionization- to Electrospray Ionization -based mass spectrometry;and (iii) from clustering to peptide sequencing;a detailed step-by-step guide is provided and exemplified using SARS-CoV-2 Spike Y839 variant and the variant of concern SARS-CoV-2 Alpha (B.1.1.7 lineage), Influenza B, and Influenza A subtypes AH1N1pdm09 and AH3N2. [ FROM AUTHOR]

I miss my Office in my home Office: Challenges with work from home

The COVID-19 pandemic has sent many employees to home offices. Some employees enjoy their home office, while for various reasons others experience challenges working from home. Qualitative investigations show that new employees who have been recruited and hired during the COVID-19 pandemic can find life in the home office quite challenging. Despite adequate technological solutions that make it possible to perform the work tasks from home, these employees want to be able to physically attend at their workplace. Our data indicate that it is important that the company not only sees technology and digitalization as "hard core" skills, but that the digital and technological are woven into other aspects of organizational life, for example, structures, culture and social interaction. New employees need to feel that they are valued, and that the business wants to establish personal and social bonds that support the development of loyalty to the company and quality of the production. These are conditions that are often tied to informal learning in the workplace. Relational development and maintenance are vital for having newcomers to not only function in the digital arena, but also within the physical sphere at the workplace. © 2022, Academic Conferences and Publishing International Limited. All rights reserved.

Comparing Parallel Surrogate-Based and Surrogate-Free Multi-objective Optimization of COVID-19 Vaccines Allocation

The simulation-based and computationally expensive problem tackled in this paper addresses COVID-19 vaccines allocation in Malaysia. The multi-objective formulation considers simultaneously the total number of deaths, peak hospital occupancy and relaxation of mobility restrictions. Evolutionary algorithms have proven their capability to handle multi-to-many objectives but require a high number of computationally expensive simulations. The available techniques to raise the challenge rely on the joint use of surrogate-assisted optimization and parallel computing to deal with computational expensiveness. On the one hand, the simulation software is imitated by a cheap-to-evaluate surrogate model. On the other hand, multiple candidates are simultaneously assessed via multiple processing cores. In this study, we compare the performance of recently proposed surrogate-free and surrogate-based parallel multi-objective algorithms through the application to the COVID-19 vaccine distribution problem. © 2022, The Author(s), under exclusive license to Springer Nature Switzerland AG.

Paleofire Data for Public Health Nursing Wildfire Planning: A Planetary Perspective

Public health Is Increasingly threatened by global warming, land use, and changing wildfire patterns that shape vegetation type, structure, and biodiversity and ultimately affect ecosystem services and our society.1 Uncontrolled large wildfires emit greenhouse gases and aerosols that induce direct and indirect climate feedback through radiative forcing in the atmosphere2 and irreversible changes of natural vegetation, thereby further accelerating climate change and associated fire risks.3 Wildfires are also harmful to human health because they create high pollution concentrations of fine particulate matter that are 2.5 micrometers or smaller (PM2.5) and concentrations of coarse particulate matter that are between 2.5 and 10 micrometers in size. When inhaled, particulate matter significantly increases a myriad of health outcomes, including overall mortality, cardiovascular mortality, and emergency department visits for respiratory morbidity, congestive heart failure, chronic obstructive pulmonary disease, and angina.4,5 Between July and October 2020, high PM2.5 concentrations from massive wildfires surrounding a large regional hospital in the western United States were associated with a 6% increase in COVID-19 cases.6 Risks for developing adverse health effects from wildfire smoke are greatest among people who are living with chronic conditions;who are experiencing intergenerational racial, economic, and housing discrimination;and who are facing social inequities from the COVID-19 pandemic.4The unprecedented recent wildfires in the western United States and their ill effects on human health and society, as well as the multiple other threats to people and places brought about by climate change, draw attention to the increasing urgency of developing new public health approaches and long-term adaptation strategies to support future population health. Observational fire data covering the past few decades give valuable information on current wildfire events.1 However, these data hardly capture long-term trends (i.e., centennial to millennial time scales) of wildfires and associated atmospheric emissions that may help to improve future fire models and thereby provide the base to adapt public health systems.3 To understand long-term trends, natural archives preserve fire history on a wide range ofspatial scales in the past beyond the period of observational fire data;examples include polar and highalpine ice cores;lake, peat, and marine sediment cores.3,8,9 Such paleofire records are based on measurements of the gaseous tracers ammonium and nitrate or particulate matter, such as levoglucosan and black carbon, and charcoal that reflect different components of wildfire-induced atmospheric smoke pollution.8,9 These paleofire records have previously identified complex regional interactions of humans, ecosystems, and climate change.3 Submicron-sized (100-500 nm in diameter) black carbon particles from wildfires and fossil fuel during the industrial era (i.e., the past 250 years) measured in ice cores and lake sediments can be used as a direct tracer for the release of harmful PM2.5 to the atmosphere.8,10 Such paleo black carbon records have been established from both polar and high-alpine glaciers on several continents and are recently developed from lake sediments.10 These found significant changes of fire activity in response to climate and human impact and enhanced pollution levels varying both in time and space. With public health nurses being well positioned to understand population health needs, planetary health, and the health consequences of wildfires, public health nurses can improve upon wildfire adaptation planning and essential public health services by understanding historical perspectives from past fires.9,11,13 Paleofire data provide direct estimates of historical atmospheric emissions from past wildfires and associated harmful concentrations of particulate matter over long distances.